Profhilo
Glowing, Hydrated, Healthy Skin.
Unlock the secret to radiant, youthful skin with Profhilo treatments. Harnessing the power of revolutionary hyaluronic acid technology, Profhilo offers unparalleled hydration and rejuvenation.
Unlike dermal fillers, profhilo does not add volume or alter facial structures. It exerts its results within the skin, stimulating collagen production and adding glow-giving hyaluronic acid. It’s commonly referred to as an ‘injectable moisturiser’ for its ability to deeply nourish and hydrate the skin. It is most commonly used to rejuvenate the face, neck, chest and hands.
Profhilo®
The Science Behind Profhilo
Profhilo® features one of the highest concentrations of hyaluronic acid on the market, attracting water in the deeper layers of the skin to boost hydration and improve skin texture. The patented NAHYCO® technology ensures prolonged activity on dermal cells, stimulating collagen and elastin production for significant improvement in skin health.
Regenerative Aesthetics
Where Hydration Meets Cellular Renewal
Profhilo® is a modern, science-led approach to skin rejuvenation that deeply hydrates and improves skin quality from within.
Profhilo® works through a process known as bio-remodelling—stimulating the skin’s own collagen and elastin production while delivering a powerful dose of hyaluronic acid, one of the body’s most vital moisture-binding molecules.
What makes Profhilo® unique is its ability to spread evenly through the skin, creating a deep reservoir of hydration that smooths fine lines, improves elasticity, and gives the skin a soft, luminous glow. Patients often describe their skin as looking firmer, plumper, and more refreshed—with a subtle yet noticeable radiance.
Profhilo® is particularly effective in areas prone to early signs of ageing and dehydration, such as the face, neck, décolletage, and hands. It’s an ideal treatment for those seeking a natural refresh—restoring dewy, youthful skin without altering your natural features.
At ORA, Profhilo® is one of our most loved regenerative treatments—celebrated for its ability to support the skin’s structure while enhancing its glow from the inside out.
Benefits of Profhilo at ORA
Improves skin hydration and elasticity
Profhilo is an advanced injectable treatment designed to deeply hydrate the skin and improve elasticity. Containing one of the highest concentrations of hyaluronic acid on the market — 64 mg per 2 mL — it delivers intense hydration exactly where the skin needs it. Clinical studies published in the Journal of Drugs in Dermatology (2016) have demonstrated that Profhilo increases skin hydration by up to 20% while significantly improving skin elasticity within four weeks. This makes it an excellent option for individuals experiencing dull, dehydrated, or crepey skin, helping to restore a soft, plump and radiant complexion.
Stimulates collagen and elastin production
Profhilo goes beyond traditional dermal fillers by stimulating the skin’s natural regenerative processes. Through bioremodeling, it activates fibroblasts to boost the production of collagen and elastin — two essential proteins that maintain skin firmness and resilience. Scientific research published in Clinical, Cosmetic and Investigational Dermatology (2019) has shown increased collagen types I and III and elastin in skin samples after treatment, leading to firmer, smoother skin over time. This makes Profhilo ideal for improving skin laxity and reducing the appearance of fine lines without adding artificial volume.
Provides rejuvenation with minimal downtime
One of the most appealing benefits of Profhilo is its ability to produce natural-looking results. The product spreads evenly beneath the skin, enhancing overall skin quality and texture without altering facial contours. Clinical trials, including those reported in J Clin Aesthet Dermatol (2017), have shown high patient satisfaction, with more than 95% reporting a fresher, more youthful appearance that still looks like themselves. Downtime is minimal, with mild swelling or bruising resolving quickly, making Profhilo the perfect choice for subtle skin rejuvenation with little disruption to daily life.
Expert Care by Our Medical Team
Prior to treatment, we will cleanse the skin to prepare it for injection. A very fine needle is used to inject Profhilo into 5 bio-aesthetic points on either side of the face.
These small bumps will appear slightly raised for up to 24 hours.
At ORA, your safety and results are our top priorities. Led by our experienced Medical Director and supported by a small skilled team of aesthetic Doctors we deliver personalised and expert care to every client.
More Information
The appointment will begin with a thorough facial assessment, which includes treatment planning. Once we have decided on the ideal treatment strategy to achieve the results you want, a very fine needle is used to make small injections, administered with little to no discomfort. There is little to no downtime after the procedure. You will start to see results from 3 days up to 2 weeks after the procedure. We will then check-in with you to ensure a perfect result. Sometimes a minor adjustment is needed to balance everything nicely and because all of our treatments are customised to you, we do recommend that new clients attend a check up visit.
Unfortunately not everyone will be a candidate for injectables. We do not recommend injectables for any pregnant or breastfeeding women. We cannot perform injectables where there is active infection at the injection site or systemically. We urge caution and recommend discussing your suitability in advance if you have any allergies, autoimmune, neuromuscular or underlying medical conditions.
Please ensure that you are feeling fit & well on the day of your treatment. Treatment cannot be performed if you are feeling unwell or have had a recent illness including flu.
We do not recommend having any other skin, beauty or aesthetic treatments in the two weeks before a peel (includes brow treatments). Please ensure that you are feeling fit & well. Treatment cannot be performed if you are feeling unwell or have had a recent illness including flu.
Read our information leaflet here for full guidance.
Nil - mild
None. This is an ideal lunchtime treatment. You will have some very small discreet bumps for approximately 20 minutes but otherwise treatment is undetectable.
Initial results are typically seen after 1 week but final results are not seen until 2 weeks post treatment. This is also the time when we recommend that new clients return to the clinic for a complimentary review to evaluate results and make any adjustments.
The effect of wrinkle relaxers is temporary and how long they last depends on the individual client. For most people, the results last between 3-4 months however runners or those who train regularly may metabolise wrinkle relaxers at a faster rate.
Pharmacologically, wrinkle relaxers start to be broken down by the body from week 7-8 post treatment. At this stage, you may notice a gradual increase in muscle activity though you will not be back to baseline until at least week 12-16 (3-4 months).
The good news is that with repeated doses the lines and wrinkles often appear less severe because the muscles being treated are being trained to relax. Wrinkle relaxer treatment is best taken as a course with repeat treatments approximately every 4-6 months. This helps to ensure that results are always progressive and natural.
